X-ray Facility for Macromolecular Crystallography

This facility is primarily supported by a grant from the Department of Science and Technology (DST) since its inception in 1983. There are five X-Ray generators with dedicated detector systems. There are four faculty members and about seventy researchers associated with this facility. This facility, the first of its kind in the country at the time of inception, is used by structural biologists from all over India. The Macromolecular crystallography laboratory is a nodal point to coordinate experiments between laboratories in India and the BM-14 beamline at ESRF, Grenoble.

Research summary:

The research themes are diverse. These include structure-function analysis of bacterial and plant lectins, non-structured proteins from rotavirus, recombinant capsids of plan viruses and transcription factors from pathogenic bacteria. The publications reporting these structural and biochemical studies are described by the associated faculty separately, or when appropriate, in the context of other facilities supported by this DBT program.